Linoleic Acid Ethyl Ester
ethyl linoleate
CAS: 544-35-4
Molecular Formula: C20H36O2
Linoleic Acid Ethyl Ester - Names and Identifiers
| Name | ethyl linoleate |
| Synonyms | ETHYL LINOLEATE ethyl linoleate ethyl linoleate, pure ETHYL LINOLEATE, NATURAL LINOLEIC ACID ETHYL ESTER Linoleic acid ethyl ester ETHYL (Z,Z)-9,12-OCTADECADIENOATE ethyl (9E,12E)-octadeca-9,12-dienoate ethyl (9Z,12Z)-octadeca-9,12-dienoate 12-octadecadienoicacid(z,z)-ethylester 9,12-Octadecadienoicacid(Z,Z)-,ethylester 9,12-Octadecadienoic acid (Z,Z)-, ethyl ester DELTA 9 CIS 12 OCTADECADIENOIC ACID ETHYL ESTER |
| CAS | 544-35-4 |
| EINECS | 208-868-4 |
| InChI | InChI=1/C20H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22-4-2/h8-9,11-12H,3-7,10,13-19H2,1-2H3/b9-8+,12-11+ |
Linoleic Acid Ethyl Ester - Physico-chemical Properties
| Molecular Formula | C20H36O2 |
| Molar Mass | 308.5 |
| Density | 0.876 g/mL at 25 °C (lit.) |
| Melting Point | <25℃ |
| Boling Point | 224 °C/17 mmHg (lit.) |
| Specific Rotation(α) | n20/D 1.455 (lit.) |
| Flash Point | 110°C |
| Solubility | Insoluble in water, soluble in ethanol and ether. It can be miscible with aliphatic solvents, oils and DMF. |
| Vapor Presure | 3.1E-06mmHg at 25°C |
| Appearance | Colorless to light yellow oily liquid |
| Color | Colourless |
| Merck | 14,3820 |
| BRN | 1727827 |
| Storage Condition | -20°C |
| Refractive Index | n20/D 1.455(lit.) |
| MDL | MFCD00009535 |
| Physical and Chemical Properties | Colorless to light yellow oily liquid. Boiling point of 212 deg C (1.6kPa),175 deg C (0.3 3千帕),133 deg C (0.13 3千帕), the relative density of 0.8865(20/4 deg C), the refractive index of 1.4675. Insoluble in water, soluble in ethanol, ether, and N,N-dimethylformamide, aliphatic solvents and oil miscible. The oxidative stability in air is strong for bisigic acid. |
Linoleic Acid Ethyl Ester - Risk and Safety
| Safety Description | S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 1 |
| RTECS | RG2185000 |
| FLUKA BRAND F CODES | 8-10 |
| HS Code | 29161500 |
Linoleic Acid Ethyl Ester - Reference
| Reference Show more | 1. [IF=6.576] Huajie Wang et al."Assessment of Variations in Round Green Tea Volatile Metabolites During Manufacturing and Effect of Second-Drying Temperature via Nontargeted Metabolomic Analysis."Frontiers in Nutrition. 2022; 9: 877132 |
Linoleic Acid Ethyl Ester - Nature
Open Data Verified Data
colorless to light yellow oily liquid. The relative density was 0.8865. Boiling Point 212 C (1.6kPa). Refractive index 4675. Insoluble in water, soluble in ethanol, ether, and aliphatic solvents, oils and N,N-= methyl formamide miscible.
Last Update：2024-01-02 23:10:35
Linoleic Acid Ethyl Ester - Preparation Method
Open Data Verified Data
with soybean oil or sunflower oil and ethanol as raw materials, using sulfuric acid as catalyst, esterification reaction was carried out to generate mixed fatty acid ethyl ester, and then the crude product was obtained by urea complexation, and the product was obtained by vacuum fractionation.
Last Update：2022-01-01 10:33:10
Linoleic Acid Ethyl Ester - Use
Open Data Verified Data
mainly used as pharmaceutical raw materials, with lower cholesterol and blood lipids, prevention and treatment of atherosclerosis.
Last Update：2022-01-01 10:33:09
Linoleic Acid Ethyl Ester - Safety
Open Data Verified Data
This product is non-toxic. Aluminium drum or glass bottle packaging. Avoid light and heat during storage.
Last Update：2022-01-01 10:33:09
Linoleic Acid Ethyl Ester - Reference Information
| update date: | 2022/11/12 10:05:38 |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | ethyl linoleate and linoleic acid have the same effect of lowering cholesterol and blood lipids, and can prevent or reduce atherosclerosis. The side reaction of ethyl linoleate is much lighter than that of linoleic acid. It can also be used as a raw material for Maitong. |
| Production method | is obtained by esterification of linoleic acid and ethanol in the presence of sulfuric acid. Linoleic acid (iodine value above 168), absolute ethanol and concentrated sulfuric acid are put into the reactor, stirred, and heated and refluxed for 4 hours. Ethanol is recovered by distillation until ethanol-free distillation. Cold, wash water until the water layer is not acidic to the wind fruit red test paper, reduce pressure distillation to remove water, and then collect 195 ℃(0.9 3千帕) fraction is the finished product. Linoleic acid can be extracted from soybean oil or sunflower oil, and the amount of linoleic acid in soybean oil is 43-56%. Soybean oil produces about 5-10% of oil feet and soap feet in the refining process. Generally, it is more economical to extract linoleic acid with leftovers. Each ton of linoleic acid consumes 5-5.9 tons of soybean oil soap feet. |
Last Update：2024-04-09 19:05:12
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View History
Linoleic Acid Ethyl Ester
N-[[P(S),2'R]-2'-脱氧-2'-氟-2'-甲基-6-O-甲基-P-苯基-5'-鸟苷酰基]-L-丙氨酸异丙酯
N4,N6-双(4-氟-3-苄基)嘧啶-4,6-二甲酰胺
甜菜碱水杨酸盐
2-tetrahydropyranone-4-boronic ester
Acrylic acid 1-adamantyl ester
哌嗪-N,N'-双(2-羟基丙烷磺酸)
1-二乙基氨基-4-氨基戊烷
N-[[P(S),2'R]-2'-脱氧-2'-氟-2'-甲基-6-O-甲基-P-苯基-5'-鸟苷酰基]-L-丙氨酸异丙酯
N4,N6-双(4-氟-3-苄基)嘧啶-4,6-二甲酰胺
甜菜碱水杨酸盐
2-tetrahydropyranone-4-boronic ester
Acrylic acid 1-adamantyl ester
哌嗪-N,N'-双(2-羟基丙烷磺酸)
1-二乙基氨基-4-氨基戊烷